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Gastroesophageal Reflux
Disease (GERD) occurs when contents of the stomach surge into the
esophagus because of a weakened lower esophageal sphincter (LES),
a muscular valve between the stomach and the esophagus. Symptoms
include a burning sensation in the chest or abdomen, indigestion,
regurgitation, difficulty in sleeping after eating, hoarseness and
sore throat. The severity of GERD depends on LES dysfunction as
well as the type and amount of fluid brought up from the stomach
and the neutralizing effect of saliva.
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Factors that may cause
GERD include foods like chocolate, peppermint, spicy fried and fatty foods,
coffee and alcoholic beverages. Studies show smoking and obesity
can also be contributing factors.
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GERD affects almost half
of the population of the United States. Forty percent of adults
(over 60 million people) suffer from a form of heartburn at least
once a month, according to a Gallup survey. About 25 million adults
suffer daily from heartburn. About 25 percent of pregnant women
suffer daily heartburn. Seven percent, or 18 million people, are
chronic sufferers who take over-the-counter or prescription medications.
GERD sufferers are 53% female and 47% male, and are concentrated
among young and middle age adults (18-59), according to HCIA Primary
Procedures, 1994. Recent studies show that GERD in infants and children
is more common than previously thought.
While the overwhelming
majority of patients suffering from GERD are treated effectively
by primary care physicians, about 0.7 percent of Americans fail
to control their symptoms with standard medical therapy.
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GERD sometimes results
in serious complications such as esophagitis, a result of too much
stomach acid in the esophagus. Esophagitis can cause esophageal
bleeding or ulcers as well as a narrowing of the esophagus from
scarring. Barrett's esophagus is a condition that causes severe
damage to the skin-like lining of the esophagus and may be a precursor
to esophageal cancer.
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Some
simple precautionary steps can be taken to reduce or eliminate GERD,
including smoking cessation and the avoidance of foods and beverages
than can weaken or irritate the LES, such as citrus, tomato products,
pepper, fried or fatty foods, chocolate, coffee and alcoholic beverages.
Doctors also suggest eating smaller-portioned meals two to three
hours before bedtime to allow the amount of stomach acid to decrease
as the stomach empties. Elevating the head of a bed or sleeping
on an angle reduces heartburn by allowing gravity to minimize reflux
of stomach contents into the esophagus. Overweight individuals often
find relief by losing weight.
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A wave of advertising
may lead people to the erroneous conclusion that heartburn relief
is as simple as popping two tablets every three hours, but GERD
should be treated as a potentially serious problem. Gastroenterologists
warn that persistent heartburn is a disease and needs attention.
If you've been to your
local pharmacy, you are aware that its shelves are packed with an
army of products that promise relief from heartburn. The choices
can be overwhelming and confusing. Antacids, like Rolaids or Tums,
neutralize pain. Coating agents, such as Gaviscon, form a layer
of foam on top of your stomach's contents to protect the esophagus
from acid. H2 blockers, like Pepcid AC and Zantac 75, block the
pain altogether.
H2 blockers were once
considered the standard therapy to treat GERD, but increasingly,
doctors are turning to newer types of prescription drugs like 'promotility'
agents, such as Propulsid, which increase the pace at which the
stomach empties, giving acid less of a chance to form, and proton-pump
inhibitors, such as Prilosec, which are stronger than H2 blockers
and virtually halt acid production.
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